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Overdosage: If you're thinking that you have taken excessive of this medicine Get hold of a poison Command Heart or emergency room directly.Signals and signs or symptoms of overdosage with promethazine HCl vary from delicate depression in the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and unexpected Demise.
Excessively substantial dosages of antihistamines, which includes promethazine HCl, in pediatric sufferers may perhaps induce sudden Dying (see OVERDOSAGE). Hallucinations and convulsions have transpired with therapeutic doses and overdoses of Promethazine HCl in pediatric patients.
Using cough syrups containing the cough suppressant dextromethorphan (DXM) rather than codeine as the principal component in lean has become ever more well-known.
Customers of lean are liable to addiction, and severe problems incorporate respiratory depression, respiratory arrest, and cardiac arrest. Lean is particularly hazardous when consumed with Liquor.
Promethazine HCl is contraindicated in comatose states, As well as in people today known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines.
The drug functions centrally and elevates the threshold for coughing. It's about equivalent to codeine in depressing the cough reflex. In therapeutic dosage dextromethorphan does not inhibit ciliary activity.
The industrial item incorporates no codeine or promethazine, but claims to "Sluggish Your Roll" with a mix of herbal components like valerian root and rose hips plus the hormone melatonin.[42][43]
Together with its cough-suppressing properties, Promethazine DM continues to be uncovered to have get more info expectorant effects. Which means that it helps loosen and expel mucus in the respiratory tract, providing aid to men and women struggling from chest congestion.
Use precisely as directed by your treatment team. Never take more than the proposed dose. It's possible you'll create tolerance to this medication in case you take it for your long time.
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Promethazine DM works by combining the effects of its two Energetic elements, promethazine and dextromethorphan, to offer thorough aid for respiratory signs and symptoms.
He was arrested as Element of an undercover narcotics investigation. Russell was booked into metropolis jail and launched soon Later on just after generating his bail.[38]
Promethazine contributes to drowsiness, while codeine may result in slouching or leaning to at least one side. Warning indications of a lean overdose include things like Excessive sedation and the possible for seizures.